New alleles are constantly accumulated during intentional cropselection. The molecular understanding of these alleles hasstimulated new genomic approaches to mapping quantitativetrait loci (QTL) and haplotype multiplicity of the genes concerned. A limited number of quantitative trait nucleotides responsible forQTL variation have been described, but an acceleration in theirrate of discovery is expected with the adoption of linkagedisequilibrium and candidate gene strategies for QTL finemapping and cloning. Additional layers of regulatory variationhave been studied that could also contribute to the molecularbasis of quantitative genetics of crop traits. Despite thisprogress, the role of marker-assisted selection in plant breedingwill ultimately depend on the genetic model underlyingquantitative variation.
Source: Current opinion in biotechnology (2003) vol. 14, p. 214-219
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